1. Slow down: I'm a pretty slow driver anyway, but even if you are a faster driver, slow down and stick to the right lane. Other drivers will appreciate it, you'll get better gas mileage, you'll be more prepared to react, and you can appreciate the scenery more.
2. Be ready to brake: Even if your teardrop is really light, don't forget that you have an extra 800 to 1,200 lbs behind you. It will take you longer to come to a full stop and since most teardrops don't require their own braking systems, you and your vehicle are in charge of coming to a complete stop.
3. Watch those curbs and bumps: While coming out of a driveway, or around a corner, watch those sidewalk curbs, planters and other bumpy things that can damage your teardrop tires or even cause axle damage. The tire fenders on my teardrop stick out and I have to really watch it if I go through a tight entrance or even a fast food drive-thru (yes, you can take your teardrop through a Taco Bell).
4. Honey, we spilled the salt: No matter how well you pack your teardrop, things are going to go flying as you motor down the highway. We've had the lid pop off our coffee and send grounds spilling over the rest of our food, the items on the inside shelves usually end up in the bed and clothes in the cupboards will tumble out when we open the doors. Each campsite stop usually requires a bit of cleaning up.
5. Check, check and double check: At nearly every rest stop, we check and re-check the tow hitch, the chains, the tires, the locks on the hatch and the windows, the electrical connections and the teardrop lights and signals. You can never be too careful.